Carbazole-Substituted Iridium Complex as a Solid State Emitter for Two-Photon Intravital Imaging

Inorg Chem. 2016 Oct 3;55(19):9586-9595. doi: 10.1021/acs.inorgchem.6b01253. Epub 2016 Sep 12.

Abstract

A tris-cyclometalated iridium complex that bears two ligands functionalized by peripheral carbazole groups combines an intense solid state emission and a significant two-photon absorption cross section in the near-infrared. After incorporation into a physiological micellar suspension, it can be used for the intravital two-photon fluorescence microscopy of cerebral vasculature.

MeSH terms

  • Animals
  • Brain / blood supply
  • Brain / diagnostic imaging
  • Carbazoles / chemical synthesis
  • Carbazoles / chemistry*
  • Coordination Complexes / chemical synthesis
  • Coordination Complexes / chemistry*
  • Fluorescence
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • Infrared Rays
  • Intravital Microscopy
  • Iridium / chemistry
  • Iridium / radiation effects*
  • Mice
  • Photons

Substances

  • Carbazoles
  • Coordination Complexes
  • Fluorescent Dyes
  • Iridium