Abstract
A method for the radioiodination of antibodies for therapy is described. The method resulted in a high efficiency of labelling (88-94%) with negligible damage to the antibody. Good localisation of labelled antibody was demonstrated. Doses of radiation to operators were very low.
MeSH terms
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Antibodies, Monoclonal / immunology
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Antibodies, Monoclonal / therapeutic use*
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Bromosuccinimide
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Drug Carriers
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Environmental Exposure
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Humans
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Immunotherapy / methods*
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Iodine Radioisotopes / therapeutic use*
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Liver Neoplasms / immunology
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Liver Neoplasms / radiotherapy
Substances
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Antibodies, Monoclonal
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Drug Carriers
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Iodine Radioisotopes
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Bromosuccinimide