Is Centrosomal Protein 70, a Centrosomal Protein with New Roles in Breast Cancer Dissemination and Metastasis, a Facilitator of Epithelial-Mesenchymal Transition?

Am J Pathol. 2017 Mar;187(3):494-497. doi: 10.1016/j.ajpath.2016.12.008. Epub 2017 Jan 19.

Author

Affiliation

¹ Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas, Universidad de Salamanca, Salamanca; and the Salamanca Institute of Biomedical Research, Hospital Universitario de Salamanca, Salamanca, Spain. Electronic address: pedro.lazo@csic.es.

PMID: 28109768
DOI: 10.1016/j.ajpath.2016.12.008

Abstract

This commentary highlights the article by Shi et al that identified centrosomal protein 70 as a key mediator of breast cancer growth and metastasis.

Copyright © 2017 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

MeSH terms

Breast Neoplasms / metabolism*
Breast Neoplasms / pathology*
Cell Cycle Proteins / metabolism*
Epithelial-Mesenchymal Transition*
Female
Humans
Microtubule-Associated Proteins / metabolism*
Models, Biological
Molecular Targeted Therapy
Neoplasm Metastasis
Phenotype

Substances

Cell Cycle Proteins
Cep70 protein, human
Microtubule-Associated Proteins