Relationship between insight and theory of mind in schizophrenia: A meta-analysis

Schizophr Res. 2017 Dec:190:11-17. doi: 10.1016/j.schres.2017.03.029. Epub 2017 Mar 14.

Abstract

Poor insight in schizophrenia has been associated with executive dysfunction and deficits in general cognitive ability. The overall outcome of available neurocognitive studies suggests that there is a significant but modest relationship between cognitive deficits and poor insight in schizophrenia. However, social cognitive abilities, particularly, theory of mind (ToM), might also play a role in poor insight in schizophrenia. A novel meta-analysis of the relationship between ToM and insight in schizophrenia was conducted. Current meta-analysis included 16 studies including 1085 patients with schizophrenia-spectrum disorders. There was a significant association between ToM and clinical insight (r=0.28, CI=0.20-0.36). By contrast, there was no significant relationship between ToM and cognitive insight. Current findings suggest that there is a small but significant relationship between ToM and clinical insight in schizophrenia. ToM impairment is one of the factors contributing to poor insight in schizophrenia.

Keywords: Insight; Schizophrenia; Theory of mind.

Publication types

  • Meta-Analysis
  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Awareness*
  • Executive Function
  • Humans
  • Perception*
  • Schizophrenic Psychology*
  • Theory of Mind*