Does aerobic exercise reduce postpartum depressive symptoms? a systematic review and meta-analysis

Br J Gen Pract. 2017 Oct;67(663):e684-e691. doi: 10.3399/bjgp17X692525. Epub 2017 Aug 30.

Abstract

Background: There is currently no specific guidance on the role of exercise in managing postpartum depression in the UK and US, and international guidance is inconsistent.

Aim: To assess the effectiveness of aerobic exercise on postpartum depressive symptoms.

Design and setting: Systematic review and meta-analysis. There was no restriction to study site or setting.

Method: The databases MEDLINE, EMBASE, Cochrane Library, PsycINFO, SportDiscus, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform were searched. Titles and abstracts, then full-text articles, were screened against inclusion criteria: RCTs measuring depressive symptoms in mothers ≤1 year postpartum; and interventions designed to increase aerobic exercise compared with usual care or other comparators. Included studies were assessed using the Cochrane Collaboration's risk of bias tool. Meta-analysis was conducted. Pre-planned subgroup analyses explored heterogeneity.

Results: Thirteen RCTs were included, with 1734 eligible participants. Exercise significantly reduced depressive symptoms when all trials were combined (standardised mean difference -0.44; 95% confidence interval = -0.75 to -0.12). Exploration of heterogeneity did not find significant differences in effect size between women with possible depression and in general postpartum populations; exercise only and exercise with co-interventions; and group exercise and exercise counselling.

Conclusion: This systematic review provides support for the effectiveness of exercise in reducing postpartum depressive symptoms. Group exercise, participant-chosen exercise, and exercise with co-interventions all may be effective interventions. These results should be interpreted with caution because of substantial heterogeneity and risk of bias.

Keywords: depression; depression, postpartum; exercise; postnatal; review, systematic.

Publication types

  • Meta-Analysis
  • Review
  • Systematic Review

MeSH terms

  • Depression, Postpartum / psychology
  • Depression, Postpartum / rehabilitation*
  • Directive Counseling
  • Exercise / psychology*
  • Female
  • Humans
  • Patient Participation
  • Treatment Outcome