Synaptopathology in autism spectrum disorders: Complex effects of synaptic genes on neural circuits

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt B):398-415. doi: 10.1016/j.pnpbp.2017.09.026. Epub 2017 Oct 3.

Authors

Xinxing Wang¹, Rachel Kery², Qiaojie Xiong³

Affiliations

¹ Department of Neurobiology & Behavior, Stony Brook University, Stony Brook, NY 11794, USA.
² Department of Neurobiology & Behavior, Stony Brook University, Stony Brook, NY 11794, USA; Medical Scientist Training Program (MSTP), Stony Brook University, Stony Brook, NY 11794, USA.
³ Department of Neurobiology & Behavior, Stony Brook University, Stony Brook, NY 11794, USA. Electronic address: Qiaojie.xiong@stonybrook.edu.

PMID: 28986278
DOI: 10.1016/j.pnpbp.2017.09.026

No abstract available

Publication types

Review

MeSH terms

Animals
Autism Spectrum Disorder / genetics*
Autism Spectrum Disorder / pathology*
Brain / metabolism
Brain / pathology*
Glutamic Acid / genetics
Glutamic Acid / metabolism
Humans
Synapses / genetics*
Synapses / pathology*
Synaptic Transmission / physiology
gamma-Aminobutyric Acid / genetics
gamma-Aminobutyric Acid / metabolism

Substances

Glutamic Acid
gamma-Aminobutyric Acid

Grants and funding

R01 NS089770/NS/NINDS NIH HHS/United States