Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

Olivia A Skrobot; Sandra E Black; Christopher Chen; Charles DeCarli; Timo Erkinjuntti; Gary A Ford; Rajesh N Kalaria; John O'Brien; Leonardo Pantoni; Florence Pasquier; Gustavo C Roman; Anders Wallin; Perminder Sachdev; Ingmar Skoog; VICCCS group; Yoav Ben-Shlomo; Anthony P Passmore; Seth Love; Patrick G Kehoe

doi:10.1016/j.jalz.2017.09.007

Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

Alzheimers Dement. 2018 Mar;14(3):280-292. doi: 10.1016/j.jalz.2017.09.007. Epub 2017 Oct 19.

Authors

Olivia A Skrobot¹, Sandra E Black², Christopher Chen³, Charles DeCarli⁴, Timo Erkinjuntti⁵, Gary A Ford⁶, Rajesh N Kalaria⁷, John O'Brien⁸, Leonardo Pantoni⁹, Florence Pasquier¹⁰, Gustavo C Roman¹¹, Anders Wallin¹², Perminder Sachdev¹³, Ingmar Skoog¹⁴; VICCCS group; Yoav Ben-Shlomo¹⁵, Anthony P Passmore¹⁶, Seth Love¹, Patrick G Kehoe¹⁷

Collaborators

VICCCS group:
F E Taragano, J Kril, M Cavalieri, K A Jellinger, G G Kovacs, S Engelborghs, C Lafosse, P H Bertolucci, S Brucki, P Caramelli, T C de Toledo Ferraz Alves, C Bocti, T Fulop, D B Hogan, G R Hsiung, A Kirk, L Leach, A Robillard, D J Sahlas, Q Guo, J Tian, L Hokkanen, H Jokinen, S Benisty, V Deramecourt, J Hauw, H Lenoir, M Tsatali, M Tsolaki, U Sundar, R F Coen, A D Korczyn, M Altieri, M Baldereschi, C Caltagirone, G Caravaglios, A Di Carlo, V Di Piero, G Gainotti, S Galluzzi, G Logroscino, P Mecocci, D V Moretti, A Padovani, T Fukui, M Ihara, T Mizuno, S Y Kim, R Akinyemi, O Baiyewu, A Ogunniyi, A Szczudlik, A J Bastos-Leite, H Firmino, J Massano, A Verdelho, L S Kruglov, M K Ikram, N Kandiah, E Arana, J Barroso-Ribal, T Calatayud, A J Cruz-Jentoft, S López-Pousa, P Martinez-Lage, M Mataro, A Börjesson-Hanson, E Englund, E J Laukka, C Qiu, M Viitanen, G J Biessels, F-E de Leeuw, T den Heijer, L G Exalto, L J Kappelle, N D Prins, E Richard, B Schmand, E van den Berg, W M van der Flier, B Bilgic, L M Allan, J Archer, J Attems, A Bayer, D Blackburn, C Brayne, R Bullock, P J Connelly, A Farrant, M Fish, K Harkness, P G Ince, P Langhorne, J Mann, F E Matthews, P Mayer, S T Pendlebury, R Perneczky, R Peters, D Smithard, B C Stephan, J E Swartz, S Todd, D J Werring, S N Wijayasiri, G Wilcock, G Zamboni, R Au, S Borson, A Bozoki, J N Browndyke, M M Corrada, P K Crane, B S Diniz, L Etcher, H Fillit, S M Greenberg, L T Grinberg, S W Hurt, M Lamar, M Mielke, B R Ott, G Perry, W J Powers, C Ramos-Estebanez, B Reed, R O Roberts, J R Romero, A J Saykin, S Seshadri, L Silbert, Y Stern, C Zarow

Affiliations

¹ Translational Health Sciences, University of Bristol, Bristol, UK.
² Sunnybrook Research Institute, University of Toronto, Ontario, Canada.
³ Department of Pharmacology, National University of Singapore, Singapore.
⁴ Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, California, USA.
⁵ Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
⁶ Divison of Medical Sciences, Oxford University, Oxford, UK.
⁷ Institute of Neuroscience, Newcastle University, Newcastle, UK.
⁸ Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, UK.
⁹ NEUROFARBA Department, University of Florence, Florence, Italy.
¹⁰ Inserm U1171, University of Lille, Lille, France.
¹¹ Methodist Neurological Institute, Houston, Texas, USA.
¹² Memory Clinic at Department of Neuropsychiatry, Sahlgrenska University Hospital, Mölndal, Sweden; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.
¹³ School of Psychiatry, University of New South Wales, Sydney, Australia; Neuropsychiatric Institute, Prince of Wales Hospital, Randwick, New South Wales, Australia.
¹⁴ Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.
¹⁵ Population Health Sciences, University of Bristol, Bristol, UK.
¹⁶ Institute of Clinical Sciences, Block B, Queens University Belfast, Belfast, UK.
¹⁷ Translational Health Sciences, University of Bristol, Bristol, UK. Electronic address: patrick.kehoe@bristol.ac.uk.

PMID: 29055812
DOI: 10.1016/j.jalz.2017.09.007

Abstract

Introduction: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2.

Methods: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI.

Results: Six survey rounds comprising 65-79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders-Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging.

Discussion: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders-Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration.

Keywords: Criteria; Delphi; Guidelines; Vascular cognitive impairment; Vascular dementia; consensus.

Progress toward standardized diagnosis of vascular cognitive impairment: Guidelines from the Vascular Impairment of Cognition Classification Consensus Study

Authors

Collaborators

Affiliations

Abstract

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