Phenotypic novelty by CRISPR in plants

Chen Liu; Panagiotis N Moschou

doi:10.1016/j.ydbio.2018.01.015

Phenotypic novelty by CRISPR in plants

Dev Biol. 2018 Mar 15;435(2):170-175. doi: 10.1016/j.ydbio.2018.01.015. Epub 2018 Jan 31.

Authors

Chen Liu¹, Panagiotis N Moschou²

Affiliations

¹ Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden.
² Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden. Electronic address: panagiotis.moschou@slu.se.

PMID: 29402392
DOI: 10.1016/j.ydbio.2018.01.015

Abstract

Genome editing by CRISPR is now routinely used in plant biology for unravelling gene functions and improving agronomical traits. CRISPR opens up the possibility of genome manipulations which would have been unthinkable a few years ago. In this perspective, we discuss and suggest CRISPR-mediated approaches for steering plant development, also highlighting potential challenges.

Keywords: Allelic variation; CRISPR-Cas9; Epigenome; Plant biotechnology; Plant development; Proteostasis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
CRISPR-Cas Systems*
DNA Shuffling
Epigenomics
Gene Editing / methods*
Gene Expression Regulation, Plant
Gene Knockout Techniques
Genes, Plant*
INDEL Mutation
Phenotype
Plants / genetics*
Plants, Genetically Modified*
Ploidies
Protein Processing, Post-Translational
Recombinational DNA Repair