Inhibiting EBV: The Key to Carefree Smooching

Shee-Mei Lok

doi:10.1016/j.immuni.2018.03.036

Inhibiting EBV: The Key to Carefree Smooching

Immunity. 2018 Apr 17;48(4):623-625. doi: 10.1016/j.immuni.2018.03.036.

Author

Shee-Mei Lok¹

Affiliation

¹ Duke-NUS Medical School, 8 College Road, Singapore 169857, and the Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543, Singapore. Electronic address: sheemei.lok@duke-nus.edu.sg.

PMID: 29669245
DOI: 10.1016/j.immuni.2018.03.036

Abstract

There are no vaccines or therapies to treat Epstein-Barr virus (EBV). Snijder et al. (2018) isolated a potent human antibody against EBV that blocks infection of both B cells and epithelial cells. Structural analysis of the antibody complexed with a viral surface protein complex identified a site that may be useful in vaccine development.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Antibodies*
B-Lymphocytes
Epithelial Cells
Herpesvirus 4, Human*
Humans

Substances

Antibodies