Biochemical Effects on the Liver of 1 Month of Alcohol Abstinence in Moderate Alcohol Consumers

I D Munsterman; M M Groefsema; G Weijers; W M Klein; D W Swinkels; J P H Drenth; A F A Schellekens; E T T L Tjwa

doi:10.1093/alcalc/agy031

Biochemical Effects on the Liver of 1 Month of Alcohol Abstinence in Moderate Alcohol Consumers

Alcohol Alcohol. 2018 Jul 1;53(4):435-438. doi: 10.1093/alcalc/agy031.

Authors

I D Munsterman¹, M M Groefsema², G Weijers³, W M Klein³, D W Swinkels⁴, J P H Drenth¹, A F A Schellekens^{5

6}, E T T L Tjwa¹

Affiliations

¹ Department of Gastroenterology & Hepatology, Radboud University Medical Centre, Geert-Grooteplein Zuid 10, HB Nijmegen, the Netherlands.
² Behavioural Science Institute, Radboud University, Comeniuslaan 4, HP, Nijmegen, the Netherlands.
³ Department of Radiology and Nuclear Medicine, Medical Ultrasound Imaging Centre, Radboud University Medical Centre, Geert-Grooteplein Zuid 10, HB Nijmegen, the Netherlands.
⁴ Department of Laboratory Medicine, Translational Metabolic Laboratory, Expertise Centre for Iron Disorders, Radboud University Medical Centre, Geert-Grooteplein Zuid 10, HB Nijmegen, the Netherlands.
⁵ Department of Psychiatry, Donders Institute for Brain Cognition and Behavior, Radboud University Medical Centre, Geert-Grooteplein Zuid 10, HB Nijmegen, the Netherlands.
⁶ Nijmegen Institute for Scientist Practitioners in Addiction (NISPA), Toernooiveld 5, ED Nijmegen, the Netherlands.

PMID: 29726886
DOI: 10.1093/alcalc/agy031

Abstract

: In this study in healthy moderate alcohol consumers, we observe that one month of alcohol abstinence results in decreased gamma-glutamyl transferase levels, which return to baseline levels after resumption of alcohol consumption.

MeSH terms

Adult
Alcohol Abstinence*
Alcohol Drinking / metabolism*
Case-Control Studies
Female
Humans
Liver / diagnostic imaging
Liver / enzymology*
Liver Function Tests
Male
Middle Aged
Prospective Studies
Young Adult
gamma-Glutamyltransferase / metabolism*

Substances

gamma-Glutamyltransferase