Real-world studies no substitute for RCTs in establishing efficacy

Lancet. 2019 Jan 19;393(10168):210-211. doi: 10.1016/S0140-6736(18)32840-X.

Authors

Hertzel C Gerstein¹, John McMurray², Rury R Holman³

Affiliations

¹ Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, ON L8S4K1, Canada. Electronic address: gerstein@mcmaster.ca.
² University of Glasgow, BHF Cardiovascular Research Centre, Glasgow, UK.
³ Diabetes Trials Unit, University of Oxford, Oxford, UK.

PMID: 30663582
DOI: 10.1016/S0140-6736(18)32840-X

No abstract available

MeSH terms

Drug Approval / methods*
Humans
Observational Studies as Topic
Pragmatic Clinical Trials as Topic
Randomized Controlled Trials as Topic / economics
Randomized Controlled Trials as Topic / standards*
Research Design / standards