NUDT15 polymorphism identified in a patient with azathioprine hypersensitivity syndrome presenting as erythema nodosum and hepatotoxicity

Br J Dermatol. 2019 Sep;181(3):631-632. doi: 10.1111/bjd.17859. Epub 2019 May 30.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Azathioprine / adverse effects*
  • Biopsy
  • Chemical and Drug Induced Liver Injury / diagnosis
  • Chemical and Drug Induced Liver Injury / genetics*
  • Chronic Urticaria / drug therapy
  • Erythema Nodosum / chemically induced
  • Erythema Nodosum / diagnosis
  • Erythema Nodosum / genetics*
  • Erythema Nodosum / pathology
  • Female
  • Humans
  • Immunosuppressive Agents / adverse effects*
  • Liver Function Tests
  • Polymorphism, Single Nucleotide
  • Pyrophosphatases / genetics*
  • Skin / drug effects
  • Skin / pathology

Substances

  • Immunosuppressive Agents
  • NUDT15 protein, human
  • Pyrophosphatases
  • Azathioprine