Gut Microbe to Brain Signaling: What Happens in Vagus…

Christine Fülling; Timothy G Dinan; John F Cryan

doi:10.1016/j.neuron.2019.02.008

Gut Microbe to Brain Signaling: What Happens in Vagus…

Neuron. 2019 Mar 20;101(6):998-1002. doi: 10.1016/j.neuron.2019.02.008.

Authors

Christine Fülling¹, Timothy G Dinan², John F Cryan³

Affiliations

¹ APC Microbiome Ireland, University College Cork, Cork, Ireland.
² APC Microbiome Ireland, University College Cork, Cork, Ireland; Department of Psychiatry and Neurobehavioural Science, University College Cork, Ireland.
³ APC Microbiome Ireland, University College Cork, Cork, Ireland; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland. Electronic address: j.cryan@ucc.ie.

PMID: 30897366
DOI: 10.1016/j.neuron.2019.02.008

Abstract

The gut microbiota has emerged as a key player in health and disease. Here we discuss the vagus nerve, which connects the visceral organs and the brain, as an important communication pathway for the gut microbiota to influence brain and behavior.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Brain / physiology*
Brain Stem
Enteric Nervous System
Gastrointestinal Microbiome / physiology*
Germ-Free Life
Humans
Intestinal Mucosa / innervation
Intestines / innervation
Vagus Nerve / physiology*