Detection of 2-amino-3-methylimidazo[4,5-f]quinoline in cigarette smoke condensate

M Yamashita; K Wakabayashi; M Nagao; S Sato; Z Yamaizumi; M Takahashi; N Kinae; I Tomita; T Sugimura

Detection of 2-amino-3-methylimidazo[4,5-f]quinoline in cigarette smoke condensate

Jpn J Cancer Res. 1986 May;77(5):419-22.

Authors

M Yamashita, K Wakabayashi, M Nagao, S Sato, Z Yamaizumi, M Takahashi, N Kinae, I Tomita, T Sugimura

PMID: 3089973

Abstract

2-Amino-3-methylimidazo[4,5-f]quinoline (IQ), which is mutagenic and carcinogenic, was found to be present in cigarette smoke condensate by liquid chromatography with an electrochemical detector and a photodiode-array detector. The amount of IQ was estimated to be 0.26 ng per cigarette.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromatography, Liquid
Mutagens / analysis*
Nicotiana*
Plants, Toxic*
Quinolines / analysis*
Smoke / analysis*

Substances

Mutagens
Quinolines
Smoke
2-amino-3-methylimidazo(4,5-f)quinoline