Building a global alliance of biofoundries

Nathan Hillson; Mark Caddick; Yizhi Cai; Jose A Carrasco; Matthew Wook Chang; Natalie C Curach; David J Bell; Rosalind Le Feuvre; Douglas C Friedman; Xiongfei Fu; Nicholas D Gold; Markus J Herrgård; Maciej B Holowko; James R Johnson; Richard A Johnson; Jay D Keasling; Richard I Kitney; Akihiko Kondo; Chenli Liu; Vincent J J Martin; Filippo Menolascina; Chiaki Ogino; Nicola J Patron; Marilene Pavan; Chueh Loo Poh; Isak S Pretorius; Susan J Rosser; Nigel S Scrutton; Marko Storch; Hille Tekotte; Evelyn Travnik; Claudia E Vickers; Wen Shan Yew; Yingjin Yuan; Huimin Zhao; Paul S Freemont

doi:10.1038/s41467-019-10079-2

Building a global alliance of biofoundries

Nat Commun. 2019 May 9;10(1):2040. doi: 10.1038/s41467-019-10079-2.

Authors

Nathan Hillson¹, Mark Caddick², Yizhi Cai³, Jose A Carrasco⁴, Matthew Wook Chang⁵, Natalie C Curach⁶, David J Bell⁷, Rosalind Le Feuvre³, Douglas C Friedman⁸, Xiongfei Fu⁹, Nicholas D Gold¹⁰, Markus J Herrgård¹¹, Maciej B Holowko^{12

13

14}, James R Johnson², Richard A Johnson¹⁵, Jay D Keasling¹, Richard I Kitney⁷, Akihiko Kondo¹⁶, Chenli Liu⁹, Vincent J J Martin¹⁰, Filippo Menolascina¹⁷, Chiaki Ogino¹⁶, Nicola J Patron⁴, Marilene Pavan¹⁸, Chueh Loo Poh⁵, Isak S Pretorius¹⁹, Susan J Rosser¹⁷, Nigel S Scrutton³, Marko Storch⁷, Hille Tekotte¹⁷, Evelyn Travnik¹¹, Claudia E Vickers^{12

13}, Wen Shan Yew⁵, Yingjin Yuan²⁰, Huimin Zhao²¹, Paul S Freemont²²

Affiliations

¹ DOE Agile BioFoundry, Emeryville, CA, 94608, USA.
² GeneMill, Institute of Integrative Biology, University of Liverpool, Liverpool, L69 7ZB, UK.
³ SYNBIOCHEM, Manchester Institute of Biotechnology and School of Chemistry, University of Manchester, Manchester, M13 9PL, UK.
⁴ Earlham Institute, Norwich Research Park, Norfolk, NR4 7UZ, UK.
⁵ NUS Synthetic Biology for Clinical and Technological Innovation (SynCTI), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117456, Singapore.
⁶ Bioplatforms Australia, Research Park Drive, Macquarie University, Macquarie Park, NSW, 2109, Australia.
⁷ London DNA Foundry, Imperial College Translation & Innovation Hub, White City Campus, 80 Wood Lane, London, W12 0BZ, UK.
⁸ Engineering Biology Research Consortium (EBRC), Emeryville, CA, 94608, USA.
⁹ Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China.
¹⁰ Centre for Applied Synthetic Biology, Concordia University, Montreal, Montreal, QC, H4B 1R6, Canada.
¹¹ The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, 2800, Kongens Lyngby, Denmark.
¹² CSIRO Synthetic Biology Future Science Platform, Canberra, ACT, 2601, Australia.
¹³ Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia.
¹⁴ Department of Molecular Sciences, Macquarie University, Macquarie, NSW, 2109, Australia.
¹⁵ Global Helix LLC, BioBricks Foundation, and Engineering Biology Research Consortium (EBRC), Emeryville, CA, 94608, USA.
¹⁶ Graduate School of Science, Technology, and Innovation, Kobe University, Kobe, 657-8501, Japan.
¹⁷ UK Centre for Mammalian Synthetic Biology SynthSys, School of Biological Sciences, University of Edinburgh, Edinburgh, EH93FF, UK.
¹⁸ DAMP Lab, Biological Design Center, Boston University, Boston, MA, 02215, USA.
¹⁹ Macquarie University, North Ryde, NSW, 2109, Australia.
²⁰ Frontier Science Center for Synthetic Biology (MOE), Tianjin University, Tianjin, People's Republic of China.
²¹ Illinois Biological Foundry for Advanced Biomanufacturing (iBioFAB), University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA.
²² London DNA Foundry, Imperial College Translation & Innovation Hub, White City Campus, 80 Wood Lane, London, W12 0BZ, UK. p.freemont@imperial.ac.uk.

Abstract

Biofoundries provide an integrated infrastructure to enable the rapid design, construction, and testing of genetically reprogrammed organisms for biotechnology applications and research. Many biofoundries are being built and a Global Biofoundry Alliance has recently been established to coordinate activities worldwide.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biomedical Research / methods*
Biotechnology / instrumentation*
Genetic Engineering*
International Cooperation*
Organisms, Genetically Modified*

Abstract

Publication types

MeSH terms

Grants and funding