Identification of the sulfotransferase iso-enzyme primarily responsible for the bio-activation of topical minoxidil

J McCoy; A Goren; T Naccarato; M Kovacevic; M Situm; V L Skudar; T Lotti

Identification of the sulfotransferase iso-enzyme primarily responsible for the bio-activation of topical minoxidil

J Biol Regul Homeost Agents. 2019;33(3):817-819.

Authors

J McCoy¹, A Goren^{1

2}, T Naccarato¹, M Kovacevic², M Situm³, V L Skudar⁴, T Lotti²

Affiliations

¹ Applied Biology, Inc., Irvine, CA, USA.
² Department of Dermatology and Venereology, University of Rome "G.Marconi", Rome, Italy.
³ Department of Dermatology and Venereology, University Hospital Center "Sestre milosrdnice", Zagreb, Croatia.
⁴ Department of Dermatology and Venereology, Zagreb School of Medicine, University of Zagreb, Croatia.

PMID: 31184104

Abstract

Pattern hair loss (i.e., androgenetic alopecia) is a common condition afflicting approximately fifty percent of men and women by the age of fifty. Currently, topical minoxidil is the only US FDA approved drug for the treatment of pattern hair loss in men and women.

Keywords: alopecia; minoxidil; pattern hair loss; sulfotransferase.

Publication types

Letter

MeSH terms

Alopecia / drug therapy*
Female
Humans
Male
Minoxidil / pharmacology*
Sulfotransferases / metabolism*

Substances

Minoxidil
Sulfotransferases