Will the long-term use of atropine eye drops in children increase the risk of dry eye?

Med Hypotheses. 2019 Nov:132:109331. doi: 10.1016/j.mehy.2019.109331. Epub 2019 Jul 26.

Abstract

In recent years, some studies indicates that atropine eye drops is one of the most effective interventions for myopia. Due to large demand, the use of low-concentration atropine eye drops to reduce myopia progression is popular in China. Considering that the underlying mechanism of atropine eye drops in controlling the progression of myopia is still unclear, it is reasonable to pay enough attention to whether the long-term use of atropine eye drops in children will increase the risk of dry eye.

MeSH terms

  • Animals
  • Atropine / administration & dosage*
  • Atropine / adverse effects*
  • Child
  • China / epidemiology
  • Disease Models, Animal
  • Disease Progression
  • Dry Eye Syndromes / chemically induced*
  • Humans
  • Myopia / drug therapy
  • Ophthalmic Solutions / administration & dosage*
  • Ophthalmic Solutions / adverse effects*
  • Patient Safety
  • Rabbits
  • Risk

Substances

  • Ophthalmic Solutions
  • Atropine