Multi-target ABC transporter modulators: what next and where to go?

Future Med Chem. 2019 Sep;11(18):2353-2358. doi: 10.4155/fmc-2019-0185. Epub 2019 Sep 13.
No abstract available

Keywords: ABC transporter inhibition; ABCB1; ABCC1; ABCG2; Alzheimer's disease; BCRP; MRP1; P-gp; activation; activator; broad-spectrum inhibitor; modulation; modulator; multi-target; multidrug resistance.

Publication types

  • Editorial

MeSH terms

  • ATP-Binding Cassette Transporters / antagonists & inhibitors*
  • ATP-Binding Cassette Transporters / metabolism
  • Alzheimer Disease / drug therapy
  • Alzheimer Disease / metabolism
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology*
  • Computer-Aided Design
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / metabolism

Substances

  • ATP-Binding Cassette Transporters
  • Antineoplastic Agents