Efficacy of salicylic acid peel in dermatophytosis

Indian J Dermatol Venereol Leprol. 2021 Sep-Oct;87(5):671-675. doi: 10.4103/ijdvl.IJDVL_853_18.

Abstract

Background: Treatment of dermatophytosis is becoming costlier and challenging.

Aims and objectives: To study the efficacy of salicylic acid peel in dermatophytosis.

Methods: Twenty-five patients (20 males and 5 females) having dermatophytosis with positive potassium hydroxide (KOH) mounts were enrolled in the study. Salicylic acid 30% was applied over the lesions weekly for 4 weeks, thereafter patients were followed up weekly for 4 weeks.

Results: Of the 25 patients, 22 (88%) patients showed clinical and microbiological cure 1 week after the last application, while the remaining 3 patients were nonresponders. Nine (41%) patients of the 22 responders showed recurrences indicating that 4 weeks' treatment is not sufficient in some patients to eradicate fungus and may require longer treatment.

Limitations: A relatively small sample size and lack of long-term follow-up are the shortcomings of our study.

Conclusion: Salicylic acid peel is a cheap and useful option in the treatment of dermatophytic infection.

Keywords: Dermatophytosis; salicylic acid peel; tinea; topical treatment.

MeSH terms

  • Adult
  • Antifungal Agents / administration & dosage*
  • Chemexfoliation*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Recurrence
  • Salicylic Acid / administration & dosage*
  • Tinea / therapy*
  • Young Adult

Substances

  • Antifungal Agents
  • Salicylic Acid