A Workflow for the Identification of Mycotoxin Metabolites Using Liquid Chromatography-Ion Mobility-Mass Spectrometry

Laura Righetti; Chiara Dall'Asta

doi:10.1007/978-1-0716-0030-6_8

A Workflow for the Identification of Mycotoxin Metabolites Using Liquid Chromatography-Ion Mobility-Mass Spectrometry

Methods Mol Biol. 2020:2084:133-144. doi: 10.1007/978-1-0716-0030-6_8.

Authors

Laura Righetti¹, Chiara Dall'Asta²

Affiliations

¹ Department of Food and Drug, University of Parma, Parma, Italy. chiara.dallasta@unipr.it.
² Department of Food and Drug, University of Parma, Parma, Italy.

PMID: 31729658
DOI: 10.1007/978-1-0716-0030-6_8

Abstract

The structural identification of phase-I and phase-II metabolites of mycotoxins is a difficult task, mostly due to the lack of standards and because of the large number of isomeric forms. Here, we describe the use of ion mobility-mass spectrometry to analyze cereal extracts and how structural information on newly discovered mycotoxins metabolites could be obtained.

Keywords: CCS; Ion mobility-mass spectrometry; Metabolite identification; Mycotoxins; TWIMS.

MeSH terms

Chromatography, High Pressure Liquid
Chromatography, Liquid* / methods
Data Analysis
Food Contamination
Ion Mobility Spectrometry* / methods
Mass Spectrometry* / methods
Mycotoxins / analysis*
Mycotoxins / isolation & purification
Mycotoxins / metabolism
Software
Triticum / microbiology
Workflow*

Substances

Mycotoxins