High Prevalence of EGFR Mutations in Lung Adenocarcinomas From Brazilian Patients Harboring the TP53 p.R337H Variant

Clin Lung Cancer. 2020 Mar;21(2):e37-e44. doi: 10.1016/j.cllc.2019.11.012. Epub 2019 Nov 28.
No abstract available

Keywords: EGFR mutation; Hereditary cancer; Li-Fraumeni syndrome; Lung adenocarcinoma; p.R337H mutation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma of Lung / epidemiology
  • Adenocarcinoma of Lung / genetics
  • Adenocarcinoma of Lung / pathology*
  • Adult
  • Aged
  • Biomarkers, Tumor / genetics*
  • Brazil / epidemiology
  • ErbB Receptors / genetics
  • Female
  • Follow-Up Studies
  • Genetic Predisposition to Disease*
  • Humans
  • Lung Neoplasms / epidemiology
  • Lung Neoplasms / genetics
  • Lung Neoplasms / pathology*
  • Male
  • Middle Aged
  • Mutation*
  • Prevalence
  • Prognosis
  • Retrospective Studies
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • Biomarkers, Tumor
  • TP53 protein, human
  • Tumor Suppressor Protein p53
  • EGFR protein, human
  • ErbB Receptors