Metabolomic Data Exploration and Analysis with the Human Metabolome Database

David S Wishart

doi:10.1007/978-1-0716-0239-3_10

Metabolomic Data Exploration and Analysis with the Human Metabolome Database

Methods Mol Biol. 2020:2104:165-184. doi: 10.1007/978-1-0716-0239-3_10.

Author

David S Wishart^{1

2}

Affiliations

¹ Department of Computing Science, University of Alberta, Edmonton, AB, Canada. dwishart@ualberta.ca.
² Department of Biological Sciences, University of Alberta, Edmonton, AB, Canada. dwishart@ualberta.ca.

PMID: 31953818
DOI: 10.1007/978-1-0716-0239-3_10

Abstract

The Human Metabolome Database (HMDB) is a comprehensive, online, digital database designed to support the analysis and interpretation of metabolomic data acquired from human and/or mammalian metabolomic studies. This chapter covers three methods or protocols pertinent to using the HMDB: (1) understanding the general layout of the HMDB; (2) exploring the contents of a typical HMDB "MetaboCard"; and (3) an example of how HMDB can be used in a metabolomics study on human glioblastoma.

Keywords: Data analysis; Database; Disease; Human; Metabolomics.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computational Biology* / methods
Data Interpretation, Statistical*
Databases, Factual*
Glioblastoma / metabolism
Humans
Metabolome
Metabolomics* / methods
User-Computer Interface
Web Browser

Grants and funding

CIHR/Canada