Development of novel liquid chromatography method for clinical monitoring of vitamin B1 metabolites and B6 status in the whole blood

Development of novel liquid chromatography method for clinical monitoring of vitamin B₁ metabolites and B₆ status in the whole blood

Talanta. 2020 May 1:211:120702. doi: 10.1016/j.talanta.2019.120702. Epub 2020 Jan 2.

¹ The Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Akademika Heyrovského, 1203, Hradec Králové, 500 05, Czech Republic; The Department of Clinical Biochemistry and Diagnostics, University Hospital, Sokolská 581, Hradec Králové, 500 05, Czech Republic.
² The Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Akademika Heyrovského, 1203, Hradec Králové, 500 05, Czech Republic; The Department of Clinical Biochemistry and Diagnostics, University Hospital, Sokolská 581, Hradec Králové, 500 05, Czech Republic. Electronic address: lenkakrcmova@seznam.cz.
³ The 3rd Internal Gerontometabolic Clinic, University Hospital, Sokolská 581, Hradec Králové, 500 05, Czech Republic.
⁴ The Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Akademika Heyrovského, 1203, Hradec Králové, 500 05, Czech Republic.

No abstract available

Keywords: HPLC; Human whole blood; Pyridoxal-5-phosphate; Thiamine derivatives; Vitamin status.