Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis

N Engl J Med. 2020 Mar 12;382(11):1068-1070. doi: 10.1056/NEJMc1915189.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / administration & dosage*
  • Biomarkers* / metabolism
  • Biopsy
  • Catechin / analogs & derivatives*
  • Catechin / therapeutic use
  • Collagen Type I / metabolism
  • Humans
  • Pulmonary Fibrosis* / drug therapy
  • Pulmonary Fibrosis* / pathology
  • Snail Family Transcription Factors / metabolism
  • Transforming Growth Factor beta1* / drug effects
  • Transforming Growth Factor beta1* / physiology

Substances

  • Antioxidants
  • Biomarkers
  • Collagen Type I
  • SNAI1 protein, human
  • Snail Family Transcription Factors
  • TGFB1 protein, human
  • Transforming Growth Factor beta1
  • Catechin
  • epigallocatechin gallate