Analysis of 92 deceased patients with COVID-19

J Med Virol. 2020 Nov;92(11):2511-2515. doi: 10.1002/jmv.25891. Epub 2020 Aug 21.

Abstract

This retrospective study aimed to analyze the clinical characteristics and complications in death cases with novel coronavirus disease-19 (COVID-19). We collected the medical records of 92 patients with COVID-19, who died in the time period ranging from 6 January 2020 to 25 February 2020, in Renmin Hospital of Wuhan University and summarized the clinical characteristics of complications. There were 91 death cases in which different complications were developed, including acute respiratory distress syndrome (ARDS) (73/91), myocardial injury (31/91), liver injury (15/91), renal insufficiency (14/91), multiple organ dysfunction syndrome (MODS) (14/91), and pneumothorax (1/91). Among these patients, 83 patients had at least one complication. However, one patient who died of recurrent gastrointestinal bleeding was not directly linked to COVID-19. The main complications of deceased patients with COVID-19 were ARDS, myocardial injury, liver injury, renal insufficiency, and MODS.

Keywords: ARDS; COVID-19; SARS-CoV-2; complications; inflammatory.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • COVID-19 / complications
  • COVID-19 / mortality*
  • COVID-19 / pathology*
  • China
  • Comorbidity
  • Female
  • Humans
  • Inflammation / pathology
  • Inflammation / virology
  • Male
  • Medical Records
  • Middle Aged
  • Respiratory Distress Syndrome / mortality
  • Respiratory Distress Syndrome / pathology*
  • Respiratory Distress Syndrome / virology
  • Retrospective Studies
  • Young Adult