New spectrum of COVID-19 manifestations in children: Kawasaki-like syndrome and hyperinflammatory response

Sirada Panupattanapong; Elizabeth B Brooks

doi:10.3949/ccjm.87a.ccc039

New spectrum of COVID-19 manifestations in children: Kawasaki-like syndrome and hyperinflammatory response

Cleve Clin J Med. 2020 Dec 31. doi: 10.3949/ccjm.87a.ccc039. Online ahead of print.

Authors

Sirada Panupattanapong¹, Elizabeth B Brooks²

Affiliations

¹ Center for Pediatric Rheumatology and Immunology, Cleveland Clinic Children's panupas@ccf.org.
² Center for Pediatric Rheumatology and Immunology, Cleveland Clinic Children's.

PMID: 32493734
DOI: 10.3949/ccjm.87a.ccc039

Abstract

In April 2020, data began emerging on Kawasaki-like syndrome and hyperinflammatory response in children with COVID-19. Since then, much has been published on the presentation of COVID-19 in pediatric patients, including its association with Kawasaki disease and the multisystem inflammatory syndrome in children (MIS-C). However, questions still remain regarding the risk factors, pathogenesis, prognosis, and specific therapy for these manifestations of COVID-19.