Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City

Eva W Cheung; Philip Zachariah; Mark Gorelik; Alexis Boneparth; Steven G Kernie; Jordan S Orange; Joshua D Milner

doi:10.1001/jama.2020.10374

Multisystem Inflammatory Syndrome Related to COVID-19 in Previously Healthy Children and Adolescents in New York City

JAMA. 2020 Jul 21;324(3):294-296. doi: 10.1001/jama.2020.10374.

Authors

Eva W Cheung¹, Philip Zachariah¹, Mark Gorelik¹, Alexis Boneparth¹, Steven G Kernie¹, Jordan S Orange¹, Joshua D Milner¹

Affiliation

¹ Department of Pediatrics, Columbia University Irving Medical Center, New York, New York.

Abstract

This case series describes clinical characteristics, treatment, and outcomes of 17 previously healthy SARS-CoV-2–infected children and adolescents with an inflammatory phenotype overlapping with but distinct from Kawasaki disease and toxic shock syndrome admitted to a New York City hospital in late April and early May 2020.

MeSH terms

Adolescent
Arrhythmias, Cardiac / virology
Betacoronavirus
COVID-19
Child
Child, Preschool
Coronavirus Infections / complications*
Cytokines / analysis
Electrocardiography
Female
Humans
Infant
Male
New York City
Pandemics
Pneumonia, Viral / complications*
SARS-CoV-2
Systemic Inflammatory Response Syndrome / diagnosis*

Substances

Cytokines

Supplementary concepts

pediatric multisystem inflammatory disease, COVID-19 related