Assignment of a gene coding for a human T-cell antigen with a molecular weight of 40,000 daltons to chromosome 17

S Osada; K R Utsumi; R Ueda; Y Akao; I Tsuge; K Nishida; J Okada; H Matsuoka; T Takahashi

doi:10.1159/000132494

Assignment of a gene coding for a human T-cell antigen with a molecular weight of 40,000 daltons to chromosome 17

Cytogenet Cell Genet. 1988;47(1-2):8-10. doi: 10.1159/000132494.

Authors

S Osada¹, K R Utsumi, R Ueda, Y Akao, I Tsuge, K Nishida, J Okada, H Matsuoka, T Takahashi

Affiliation

¹ Department of Pediatrics, Nagoya University School of Medicine, Japan.

PMID: 3258561
DOI: 10.1159/000132494

Abstract

Hybrid human-mouse T-cell clones reactive with Tp40 antibody, which detects cluster of differentiation (CD)7 antigen on human T lymphocytes, were established. Karyotype analysis showed that human chromosome 17 was essential for the expression of CD7 antigen. The presence of this chromosome was confirmed by enzyme analysis of galactokinase, which is coded by a gene on human chromosome 17.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antigens, Differentiation, T-Lymphocyte / genetics*
Chromosome Mapping
Chromosomes, Human, Pair 17*
Humans
Hybrid Cells
Mice
Molecular Weight

Substances

Antigens, Differentiation, T-Lymphocyte