Synthetic cannabinoids induce acute lung inflammation via cannabinoid receptor 1 activation

Charles N Zawatsky; Jasmina Abdalla; Resat Cinar

doi:10.1183/23120541.00121-2020

Synthetic cannabinoids induce acute lung inflammation via cannabinoid receptor 1 activation

ERJ Open Res. 2020 Aug 17;6(3):00121-2020. doi: 10.1183/23120541.00121-2020. eCollection 2020 Jul.

Authors

Charles N Zawatsky^{1

2}, Jasmina Abdalla^{1

2}, Resat Cinar¹

Affiliations

¹ Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD, USA.
² These authors contributed equally.

Abstract

Synthetic cannabinoids (SCs) induce a pro-inflammatory condition by activating cannabinoid receptor 1 (CB₁R) in the lungs of mice, which raises a potential therapeutic use of CB₁R antagonists in SC-induced lung disease resulting in hospitalisation https://bit.ly/31bWw4Q.