Five cases of leishmaniasis in genital organs are exposed. The patients are males, farmers, with less than 30 years old (except one), residents of high leishmaniasis incidence zones. The majority of lesions were in penis, and of scabies ulcer type, destructive, painless and of slow evolution. In this cases generally, the clinic diagnosis was difficult to corroborate by the habitual laboratory methods and we insist that the principal differential diagnosis are the neoplastic process of the zone. The suspicion high index is important even to proceed to the therapeutic test and solve this kind of problems.