Prolonged and Late-Onset Symptoms of Coronavirus Disease 2019

Yusuke Miyazato; Shinichiro Morioka; Shinya Tsuzuki; Masako Akashi; Yasuyo Osanai; Keiko Tanaka; Mari Terada; Michiyo Suzuki; Satoshi Kutsuna; Sho Saito; Kayoko Hayakawa; Norio Ohmagari

doi:10.1093/ofid/ofaa507

Prolonged and Late-Onset Symptoms of Coronavirus Disease 2019

Open Forum Infect Dis. 2020 Oct 21;7(11):ofaa507. doi: 10.1093/ofid/ofaa507. eCollection 2020 Nov.

Authors

Yusuke Miyazato¹, Shinichiro Morioka^{1

2

3}, Shinya Tsuzuki^{3

4}, Masako Akashi¹, Yasuyo Osanai¹, Keiko Tanaka¹, Mari Terada¹, Michiyo Suzuki¹, Satoshi Kutsuna¹, Sho Saito^{1

2}, Kayoko Hayakawa^{1

3}, Norio Ohmagari^{1

3}

Affiliations

¹ Disease Control and Prevention Center, National Center for Global Health and Medicine Hospital, Tokyo, Japan.
² Emerging and Reemerging Infectious Diseases, Graduate School of Medicine, Tohoku University, Sendai, Japan.
³ AMR Clinical Reference Center, National Center for Global Health and Medicine Hospital, Tokyo, Japan.
⁴ Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.

Abstract

Some patients who recover from coronavirus disease 2019 (COVID-19) have prolonged symptoms such as dyspnea, fatigue, cough, and dysosmia for longer than 120 days after symptom onset. In addition, some patients who recovered from COVID-19 reported hair loss a few months after the onset of the disease. Alopecia is a late-onset symptom of COVID-19. The cause of alopecia is unknown; however, androgenic alopecia and telogen effluvium are possible causes.

Keywords: COVID-19; alopecia; duration; late-onset symptoms; prolonged symptoms.