Plasticity in growth behavior of patients' acute myeloid leukemia stem cells growing in mice

Sarah Ebinger; Christina Zeller; Michela Carlet; Daniela Senft; Johannes W Bagnoli; Wen-Hsin Liu; Maja Rothenberg-Thurley; Wolfgang Enard; Klaus H Metzeler; Tobias Herold; Karsten Spiekermann; Binje Vick; Irmela Jeremias

doi:10.3324/haematol.2019.226282

Plasticity in growth behavior of patients' acute myeloid leukemia stem cells growing in mice

Haematologica. 2020 Dec 1;105(12):2855-2860. doi: 10.3324/haematol.2019.226282.

Affiliations

¹ Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Zentrum München, Germany.
² Anthropology and Human Genomics, Dept. of Biology II, Ludwig-Maximilians-University, Martinsried.
³ Laboratory for Leukemia Diagnostics, Department of Medicine III, University Hospital, LMU Munich.
⁴ Department of Medicine III, University Hospital, LMU Munich.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Cycle
Cell Proliferation
Humans
Leukemia, Myeloid, Acute*
Mice
Neoplastic Stem Cells
Stem Cells

Grants and funding

Funding: the work was supported by grants from the European Research Council Consolidator Grant 681524; a Mildred Scheel Professorship by German Cancer Aid; German Research Foundation (DFG) Collaborative Research Center 1243 “Genetic and Epigenetic Evolution of Hematopoietic Neoplasms”, projects A05, A06 (to KHM), A07 (to KS) and A14 (to JWB and WE), and associate member (TH); DFG proposal MA 1876/13-1; Bettina Bräu Stiftung and Dr. Helmut Legerlotz Stiftung (all to IJ, if not indicated differently). This work was further supported by the Physician Scientists Grant (G-509200-004) from the Helmholtz Zentrum München to TH.