Assessment of health-related quality-of-life in patients with chronic Rhinosinusitis - Validation of the German Sino-Nasal Outcome Test-22 (German-SNOT-22)

D Riedl; D Dejaco; T B Steinbichler; V Innerhofer; T Gottfried; L Bektic-Tadic; A I Giotakis; G Rumpold; H Riechelmann

doi:10.1016/j.jpsychores.2020.110316

Assessment of health-related quality-of-life in patients with chronic Rhinosinusitis - Validation of the German Sino-Nasal Outcome Test-22 (German-SNOT-22)

J Psychosom Res. 2021 Jan:140:110316. doi: 10.1016/j.jpsychores.2020.110316. Epub 2020 Nov 24.

Authors

D Riedl¹, D Dejaco², T B Steinbichler³, V Innerhofer³, T Gottfried³, L Bektic-Tadic³, A I Giotakis³, G Rumpold¹, H Riechelmann³

Affiliations

¹ Department of Medical Psychology, Medical University of Innsbruck, Schöpfstr. 23a, 6020 Innsbruck, Tyrol, Austria.
² Department of Otorhinolaryngology - Head and Neck Surgery, Medical University of Innsbruck, Anichstr. 35, 6020 Innsbruck, Tyrol, Austria. Electronic address: daniel.dejaco@i-med.ac.at.
³ Department of Otorhinolaryngology - Head and Neck Surgery, Medical University of Innsbruck, Anichstr. 35, 6020 Innsbruck, Tyrol, Austria.

PMID: 33271403
DOI: 10.1016/j.jpsychores.2020.110316

Abstract

Purpose: The Sino-Nasal-Outcome-Test-22 (SNOT-22) represents the reference questionnaire to assess symptoms, health-related quality-of-life (HRQOL) and treatment-response in patients with chronic rhinosinusitis (CRS). The SNOT-22 has been validated for various languages, yet no validation is available for the German version. Thus, we provide a validation of the SNOT-22 for German.

Methods: In this prospective observational study 139 CRS-patients and 36 control-participants were included. CRS-patients completed the German-SNOT-22 before treatment (T0) and four (T1), twelve (T2) and 48 weeks after inclusion (T3). At T0, Mackay-Naclerio-, Lund-Mackay- and Brief-Symptom-Inventory-18 (BSI-18) scores were collected as external reference for the German-SNOT-22 and its subscales. At T1, T2, and T3 health-transition-items (HTIs) were raised to explore responsivity. Control-participants completed the German-SNOT-22 at T0. Reliability (internal consistency, item-total correlation), validity (concurrent validity, discriminatory validity) and responsiveness (distribution- and anchor-based) were explored for the German-SNOT-22.

Results: At T0, the mean German-SNOT-22 total-score for CRS patients was 38.0 (± 20.9) and responded to treatment (T1 = 26.3 ± 19.1; T2 = 25.8 ± 20.6; T3 = 20.5 ± 16.3). For control-participants, the mean total-score at T0 was 15.1 (±10.9). The German-SNOT-22 was reliable (excellent internal consistency α = 0.93; good overall item-total correlations r = 0.39-0.85), valid (significant correlations between Mackay-Naclerio-, Lund-Mackay- and BSI-18 scores, all r > 0.39, p < 0.01) and responsive (significant correlations between HTIs and mean change in German-SNOT-22 total-score F = 9.57, p < 0.001).

Conclusion: The German-SNOT-22 validated here matches the original SNOT-22. It is a reliable, valid and responsive questionnaire to assess symptoms, HRQOL and treatment-response in CRS-patients. Good psychometric properties were observed.

Keywords: Health-related-quality-of-life; Paranasal sinus diseases; Patient reported outcome measures; Sino-Nasal-Outcome-Test-22; Sinusitis; Validation-study.

MeSH terms

Adolescent
Adult
Aged
Chronic Disease
Female
Germany
Humans
Language
Male
Middle Aged
Prospective Studies
Psychometrics / methods*
Quality of Life / psychology*
Reproducibility of Results
Rhinitis / diagnosis*
Rhinitis / psychology*
Sino-Nasal Outcome Test*
Sinusitis / diagnosis
Sinusitis / psychology*
Young Adult