The Role of Nutrition During the COVID-19 Pandemic: What We Know

Endocr Metab Immune Disord Drug Targets. 2021;21(11):1982-1992. doi: 10.2174/1871530321666210114154401.

Abstract

Background: Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) (COVID-19) infection provokes serious clinical consequences, which in many situations need hospitalization of the patient in Intensive Care Unit. Additionally, SARS-COV-2 infection can indirectly cause deaths in aged individuals as well as in patients with co-morbidities.

Objective: To evaluate the effects of nutrition during the COVID-19 pandemic in both hospitalized patients and the general population.

Methods: Authors searched Medline (PubMed), Web of Science, EMBASE, Cochrane Library, Google, and Institutional websites for medical subheadings terms and free full text referred to "SARS-CoV-2", COVID-19", "nutrition", "immune system", before 31st July 2020.

Results: A total of 20 articles describing different nutritional interventions for patients with SARS-- CoV-2 infection focusing on the general population have been included. Of these, 6 studies are dealing with nutritional interventions for patients with SARS-CoV2 infection. The others are focalized on a potential beneficial effect exerted by a Mediterranean diet (MD), related to the supplementation of micronutrients and vitamins.

Conclusion: A correct lifestyle, including the consumption of nutrients largely present in MD, may be beneficial for preventing or improving prognosis in the SARS-CoV-2 infection.

Keywords: Immune system; SARS-CoV-2; mediterranean diet.; nutrition; patients; prevention.

Publication types

  • Systematic Review

MeSH terms

  • COVID-19 / immunology
  • COVID-19 / physiopathology
  • COVID-19 / therapy*
  • COVID-19 / virology
  • Diet, Healthy
  • Diet, Mediterranean
  • Dietary Supplements
  • Hospitalization
  • Host-Pathogen Interactions
  • Humans
  • Nutrition Therapy* / adverse effects
  • Nutritional Status*
  • Nutritive Value
  • Risk Assessment
  • Risk Factors
  • Risk Reduction Behavior
  • SARS-CoV-2 / immunology
  • SARS-CoV-2 / pathogenicity*
  • Treatment Outcome