Performance of the BinaxNOW coronavirus disease 2019 (COVID-19) Antigen Card test relative to the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) real-time reverse transcriptase polymerase chain reaction (rRT-PCR) assay among symptomatic and asymptomatic healthcare employees

Infect Control Hosp Epidemiol. 2022 Jan;43(1):99-101. doi: 10.1017/ice.2021.20. Epub 2021 Jan 25.

Abstract

The sensitivity of the BinaxNOW coronavirus disease 2019 (COVID-19) Ag Card test (BinaxNOW) was 51.6% among asymptomatic healthcare employees relative to real-time reverse transcriptase polymerase chain reaction (rRT-PCR). The odds of a positive BinaxNOW test decreased as cycle threshold value increased. BinaxNOW could facilitate rapid detection and isolation of asymptomatically infected persons in some settings while rRT-PCR results are pending.

MeSH terms

  • Antigens, Viral / analysis*
  • Asymptomatic Infections
  • COVID-19 Nucleic Acid Testing*
  • COVID-19 Testing / methods*
  • COVID-19* / diagnosis
  • Health Personnel
  • Humans
  • RNA-Directed DNA Polymerase
  • Real-Time Polymerase Chain Reaction
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sensitivity and Specificity

Substances

  • Antigens, Viral
  • RNA-Directed DNA Polymerase