Special Issue: DNA Repair and Somatic Repeat Expansion in Huntington's Disease

Lesley Jones; Vanessa C Wheeler; Christopher E Pearson

doi:10.3233/JHD-219001

Special Issue: DNA Repair and Somatic Repeat Expansion in Huntington's Disease

J Huntingtons Dis. 2021;10(1):3-5. doi: 10.3233/JHD-219001.

Authors

Lesley Jones¹, Vanessa C Wheeler^{2

3}, Christopher E Pearson^{4

5}

Affiliations

¹ Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, UK.
² Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
³ Department of Neurology, Harvard Medical School, Boston, MA, USA.
⁴ Program of Genetics & Genome Biology, The Hospital for Sick Children, The Peter Gilgan Centre for Research and Learning, Toronto, Ontario, Canada.
⁵ University of Toronto, Program of Molecular Genetics.

No abstract available

Keywords: DNA repair; Huntington’s disease; Repeat expansion disorders; drug targets; genetic modifiers of Huntington’s disease; neurodegeneration; short tandem repeat; somatic repeat expansion.

Publication types

Introductory Journal Article

MeSH terms

Animals
DNA Repair / genetics*
Humans
Huntingtin Protein / genetics*
Huntington Disease / genetics*
Huntington Disease / therapy*
Trinucleotide Repeat Expansion / genetics*

Substances

HTT protein, human
Huntingtin Protein