A patient with a germline GATA2 mutation and primary myelofibrosis

Blood Adv. 2021 Feb 9;5(3):791-795. doi: 10.1182/bloodadvances.2020003401.

Authors

Cyrill V Rütsche¹, Eugenia Haralambieva², Veronika Lysenko¹, Stefan Balabanov¹, Alexandre P A Theocharides¹

Affiliations

¹ Department of Medical Oncology and Hematology, University Hospital Zurich-University of Zurich, Zurich, Switzerland; and.
² Institute of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.

Abstract

First description of a patient with a germline GATA2 mutation and diagnosis of primary myelofibrosis.
Development of bone marrow failure on a Janus kinase inhibitor.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

GATA2 Transcription Factor / genetics
Germ Cells
Germ-Line Mutation
Humans
Primary Myelofibrosis* / genetics

Substances

GATA2 Transcription Factor
GATA2 protein, human