The Increasing Proportion of Early-Stage Pancreatic Cancer between 2004-2013: A SEER Analysis

Cancer Invest. 2021 Mar;39(3):229-234. doi: 10.1080/07357907.2021.1888386. Epub 2021 Feb 18.

Abstract

Pancreatic cancer will become the second leading cause of cancer-related death in the United States by 2030. Survival improves when it is identified at an early-stage and resected. Increasing public attention and cross-section imaging may shift detection to earlier stages. We found a small total increase in the proportion of stage-I cancer relative to all stages and a significant increase compared to distant disease in the Surveillance, Epidemiology, and End Results (SEER) database. Despite this, our ability to screen and identify early-stage disease is still lacking. Additional research and population-based interventions are necessary to improve early detection.

Keywords: Pancreatic neoplasms; digestive system neoplasms; epidemiology; pancreas; public health.

MeSH terms

  • Adenocarcinoma / epidemiology*
  • Adenocarcinoma / pathology*
  • Aged
  • Aged, 80 and over
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreatic Neoplasms / epidemiology*
  • Pancreatic Neoplasms / pathology*
  • SEER Program
  • United States / epidemiology