Mitochondrial quality control: Just walk away

Cell Metab. 2021 Jun 1;33(6):1069-1071. doi: 10.1016/j.cmet.2021.05.011.

Abstract

The repair and removal of damaged mitochondria is essential for sustaining cellular and tissue homeostasis. Now in Cell, Jiao et al. (2021) describe a novel mechanism of such quality control in which damaged mitochondria move to the plasma membrane where they are "packaged" and left behind the trailing edge of migrating cells.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Homeostasis
  • Mitochondria*