CRISPR-Cas9 can cause chromothripsis

Nat Genet. 2021 Jun;53(6):768-769. doi: 10.1038/s41588-021-00881-4.

Author

Fyodor D Urnov^{1

2}

Affiliations

¹ Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, USA. urnov@berkeley.edu.
² Innovative Genomics Institute, Berkeley, CA, USA. urnov@berkeley.edu.

PMID: 34103715
DOI: 10.1038/s41588-021-00881-4

No abstract available

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MeSH terms

CRISPR-Cas Systems* / genetics
Chromothripsis*
Clustered Regularly Interspaced Short Palindromic Repeats / genetics
Gene Editing
Humans