COVID-19 in patients with CLL: improved survival outcomes and update on management strategies

Lindsey E Roeker; Toby A Eyre; Meghan C Thompson; Nicole Lamanna; Alexander R Coltoff; Matthew S Davids; Peter O Baker; Lori Leslie; Kerry A Rogers; John N Allan; Raul Cordoba; Alberto Lopez-Garcia; Darko Antic; John M Pagel; Nicolas Martinez-Calle; José Antonio García-Marco; Jose-Ángel Hernández-Rivas; Fatima Miras; Catherine C Coombs; Anders Österborg; Lotta Hansson; Amanda N Seddon; Javier López Jiménez; Matthew R Wilson; Dima El-Sharkawi; Daniel Wojenski; Shuo Ma; Talha Munir; Susana Valenciano; Erlene Seymour; Paul M Barr; Jeffrey Pu; Piers E M Patten; Guilherme F Perini; Scott F Huntington; Helen Parry; Suchitra Sundaram; Alan Skarbnik; Manali Kamdar; Ryan Jacobs; Harriet Walter; Renata Walewska; Angus Broom; Sonia Lebowitz; Krista M Isaac; Craig A Portell; Inhye E Ahn; Chaitra S Ujjani; Mazyar Shadman; Sigrid S Skånland; Elise A Chong; Anthony R Mato

doi:10.1182/blood.2021011841

COVID-19 in patients with CLL: improved survival outcomes and update on management strategies

Blood. 2021 Nov 4;138(18):1768-1773. doi: 10.1182/blood.2021011841.

Authors

Lindsey E Roeker¹, Toby A Eyre², Meghan C Thompson¹, Nicole Lamanna³, Alexander R Coltoff³, Matthew S Davids⁴, Peter O Baker⁴, Lori Leslie⁵, Kerry A Rogers⁶, John N Allan⁷, Raul Cordoba⁸, Alberto Lopez-Garcia⁸, Darko Antic⁹, John M Pagel¹⁰, Nicolas Martinez-Calle¹¹, José Antonio García-Marco¹², Jose-Ángel Hernández-Rivas¹³, Fatima Miras¹⁴, Catherine C Coombs¹⁵, Anders Österborg¹⁶, Lotta Hansson¹⁶, Amanda N Seddon¹⁷, Javier López Jiménez¹⁸, Matthew R Wilson¹⁹, Dima El-Sharkawi²⁰, Daniel Wojenski²¹, Shuo Ma²¹, Talha Munir²², Susana Valenciano²³, Erlene Seymour²⁴, Paul M Barr²⁵, Jeffrey Pu²⁶, Piers E M Patten²⁷, Guilherme F Perini²⁸, Scott F Huntington²⁹, Helen Parry³⁰, Suchitra Sundaram³¹, Alan Skarbnik³², Manali Kamdar³³, Ryan Jacobs³⁴, Harriet Walter³⁵, Renata Walewska³⁶, Angus Broom³⁷, Sonia Lebowitz¹, Krista M Isaac³⁸, Craig A Portell³⁸, Inhye E Ahn³⁹, Chaitra S Ujjani⁴⁰, Mazyar Shadman⁴⁰, Sigrid S Skånland⁴¹, Elise A Chong⁴², Anthony R Mato¹

Affiliations

¹ Memorial Sloan Kettering Cancer Center, New York, NY.
² Oxford University Hospitals, National Health Service (NHS) Foundation Trust, Oxford, United Kingdom.
³ Columbia University Medical Center, New York, NY.
⁴ Dana-Farber Cancer Institute, Boston, MA.
⁵ John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ.
⁶ The Ohio State University, Columbus, OH.
⁷ New York-Presbyterian Hospital, Weill Cornell Medicine, New York, NY.
⁸ Fundacion Jimenez Diaz University Hospital, Madrid, Spain.
⁹ Clinical Center Serbia, University of Belgrade, Belgrade, Serbia.
¹⁰ Swedish Cancer Institute, Seattle, WA.
¹¹ Nottingham University Hospitals, NHS Trust, Nottingham, United Kingdom.
¹² Hospital Puerta de Hierro Majadahonda, Madrid, Spain.
¹³ Hospital Infanta Leonor, Madrid, Spain.
¹⁴ Hospital Doce de Octubre, Madrid, Spain.
¹⁵ The University of North Carolina Cancer Center, Chapel Hill, NC.
¹⁶ Karolinska Institute, Solna, Sweden.
¹⁷ Rush University Medical Center, Chicago, IL.
¹⁸ Hospital Ramon y Cajal, Madrid, Spain.
¹⁹ Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom.
²⁰ The Royal Marsden Hospital, London, United Kingdom.
²¹ Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL.
²² St James's University Hospital, Leeds, United Kingdom.
²³ Hospital Principe de Asturias, Alcala de Henares, Madrid, Spain.
²⁴ Karmanos Cancer Institute, Wayne State University, Detroit, MI.
²⁵ University of Rochester Wilmot Cancer Institute, Rochester, NY.
²⁶ Upstate Cancer Center, Syracuse, NY.
²⁷ Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Science, King's College London, United Kingdom.
²⁸ Hospital Israelita Albert Einstein, São Paulo, Brazil.
²⁹ Yale University, New Haven, CT.
³⁰ Medical and Dental Sciences, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
³¹ Roswell Park Cancer Institute, Buffalo, NY.
³² Novant Health, Charlotte, NC.
³³ University of Colorado Cancer Center, Aurora, CO.
³⁴ Levine Cancer Institute/Atrium Health, Charlotte, NC.
³⁵ Leicester Royal Infirmary, Leicester, United Kingdom.
³⁶ Royal Bournemouth Hospital, Bournemouth, United Kingdom.
³⁷ Western General Hospital, Edinburgh, United Kingdom.
³⁸ Emily Couric Clinical Cancer Center, Charlottesville, VA.
³⁹ National Heart, Lung, and Blood Institute, Bethesda, MD.
⁴⁰ Fred Hutchinson Cancer Research Center, Seattle, WA.
⁴¹ Department of Cancer Immunology, Institute for Cancer Research, Oslo University, Oslo, Norway; and.
⁴² Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural

MeSH terms

Adult
Aged
Aged, 80 and over
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Antiviral Agents / therapeutic use*
COVID-19 / complications
COVID-19 / mortality*
COVID-19 / therapy
COVID-19 / virology
Disease Management
Drug Therapy, Combination
Female
Follow-Up Studies
Humans
Leukemia, Lymphocytic, Chronic, B-Cell / epidemiology
Leukemia, Lymphocytic, Chronic, B-Cell / mortality*
Leukemia, Lymphocytic, Chronic, B-Cell / therapy
Leukemia, Lymphocytic, Chronic, B-Cell / virology
Male
Middle Aged
Prognosis
Retrospective Studies
SARS-CoV-2 / drug effects*
SARS-CoV-2 / isolation & purification
Survival Rate
United States / epidemiology

Substances

Antiviral Agents

Publication types

MeSH terms

Substances

Grants and funding