TSC1 Mosaicism Leading to Subependymal Giant Cell Astrocytoma but Not Tuberous Sclerosis Complex

Pediatr Neurol. 2021 Oct:123:38-39. doi: 10.1016/j.pediatrneurol.2021.07.008. Epub 2021 Jul 23.

Authors

Adriana Hall¹, Grant Westlake¹, Brittany Parker Short¹, Matthew Pearson², Kevin C Ess³

Affiliations

¹ Division of Pediatric Neurology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.
² University of South Carolina School of Medicine, Greenville, South Carolina.
³ Division of Pediatric Neurology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: kevin.ess@vanderbilt.edu.

PMID: 34391197
PMCID: PMC8429189
DOI: 10.1016/j.pediatrneurol.2021.07.008

No abstract available

Keywords: Mosaic; SEGA; TSC; mTOR.

Publication types

Case Reports
Letter
Research Support, N.I.H., Extramural

MeSH terms

Astrocytoma / diagnosis*
Astrocytoma / surgery
Brain Neoplasms / diagnosis*
Brain Neoplasms / surgery
Child
Humans
Male
Mosaicism*
TOR Serine-Threonine Kinases
Tuberous Sclerosis Complex 1 Protein / genetics*

Substances

TSC1 protein, human
Tuberous Sclerosis Complex 1 Protein
MTOR protein, human
TOR Serine-Threonine Kinases

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