Chaperone-Mediated Autophagy of eNOS in Myocardial Ischemia-Reperfusion Injury

Circ Res. 2021 Oct 29;129(10):930-945. doi: 10.1161/CIRCRESAHA.120.317921. Epub 2021 Sep 22.

Abstract

[Figure: see text].

Keywords: chaperone-mediated autophagy; hypoxia; lysosome; reperfusion injury.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Autophagy*
  • Cells, Cultured
  • Glutathione / metabolism
  • HSC70 Heat-Shock Proteins / metabolism
  • Humans
  • Lysosomal-Associated Membrane Protein 2 / metabolism
  • Mice
  • Mice, Inbred C57BL
  • Myocardial Reperfusion Injury / metabolism*
  • Nitric Oxide Synthase Type III / metabolism*

Substances

  • HSC70 Heat-Shock Proteins
  • Hspa8 protein, mouse
  • Lysosomal-Associated Membrane Protein 2
  • Nitric Oxide Synthase Type III
  • Glutathione