Acute Myocarditis Following COVID-19 mRNA Vaccination in Adults Aged 18 Years or Older

Anthony Simone; John Herald; Aiyu Chen; Neil Gulati; Albert Yuh-Jer Shen; Bruno Lewin; Ming-Sum Lee

doi:10.1001/jamainternmed.2021.5511

Acute Myocarditis Following COVID-19 mRNA Vaccination in Adults Aged 18 Years or Older

JAMA Intern Med. 2021 Dec 1;181(12):1668-1670. doi: 10.1001/jamainternmed.2021.5511.

Authors

Anthony Simone¹, John Herald¹, Aiyu Chen², Neil Gulati³, Albert Yuh-Jer Shen¹, Bruno Lewin⁴, Ming-Sum Lee¹

Affiliations

¹ Department of Cardiology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.
² Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California.
³ Department of Cardiology, Kaiser Permanente Orange County Medical Center, Irvine, California.
⁴ Department of Family Medicine, Kaiser Permanente Los Angeles Medical Center, Los Angeles, California.

Abstract

This cohort study examines the incidence and clinical outcomes of acute myocarditis among adults following mRNA vaccination in an integrated health care system in the US.

MeSH terms

2019-nCoV Vaccine mRNA-1273
Adolescent
Adult
Autoantigens / immunology*
BNT162 Vaccine
COVID-19 / epidemiology
COVID-19 / immunology
COVID-19 / prevention & control*
COVID-19 Vaccines / administration & dosage
COVID-19 Vaccines / adverse effects*
COVID-19 Vaccines / immunology
California / epidemiology
Female
Humans
Male
Myocarditis / chemically induced*
Myocarditis / diagnosis
RNA, Messenger
SARS-CoV-2 / genetics
SARS-CoV-2 / immunology*
Vaccination / adverse effects*

Substances

Autoantigens
COVID-19 Vaccines
RNA, Messenger
2019-nCoV Vaccine mRNA-1273
BNT162 Vaccine