ECCO Guidelines on Therapeutics in Ulcerative Colitis: Surgical Treatment

Antonino Spinelli; Stefanos Bonovas; Johan Burisch; Torsten Kucharzik; Michel Adamina; Vito Annese; Oliver Bachmann; Dominik Bettenworth; Maria Chaparro; Wladyslawa Czuber-Dochan; Piotr Eder; Pierre Ellul; Catarina Fidalgo; Gionata Fiorino; Paolo Gionchetti; Javier P Gisbert; Hannah Gordon; Charlotte Hedin; Stefan Holubar; Marietta Iacucci; Konstantinos Karmiris; Konstantinos Katsanos; Uri Kopylov; Peter L Lakatos; Theodore Lytras; Ivan Lyutakov; Nurulamin Noor; Gianluca Pellino; Daniele Piovani; Edoardo Savarino; Francesco Selvaggi; Bram Verstockt; Glen Doherty; Tim Raine; Yves Panis

doi:10.1093/ecco-jcc/jjab177

ECCO Guidelines on Therapeutics in Ulcerative Colitis: Surgical Treatment

J Crohns Colitis. 2022 Feb 23;16(2):179-189. doi: 10.1093/ecco-jcc/jjab177.

Authors

Antonino Spinelli¹, Stefanos Bonovas², Johan Burisch³, Torsten Kucharzik⁴, Michel Adamina^{5

6}, Vito Annese⁷, Oliver Bachmann^{8

9}, Dominik Bettenworth¹⁰, Maria Chaparro¹¹, Wladyslawa Czuber-Dochan¹², Piotr Eder¹³, Pierre Ellul¹⁴, Catarina Fidalgo¹⁵, Gionata Fiorino¹⁶, Paolo Gionchetti¹⁷, Javier P Gisbert¹¹, Hannah Gordon¹⁸, Charlotte Hedin¹⁹, Stefan Holubar²⁰, Marietta Iacucci²¹, Konstantinos Karmiris²², Konstantinos Katsanos²³, Uri Kopylov²⁴, Peter L Lakatos^{25

26}, Theodore Lytras²⁷, Ivan Lyutakov²⁸, Nurulamin Noor²⁹, Gianluca Pellino³⁰, Daniele Piovani³¹, Edoardo Savarino³², Francesco Selvaggi³³, Bram Verstockt³⁴, Glen Doherty³⁵, Tim Raine²⁹, Yves Panis³⁶

Affiliations

¹ Department of Biomedical Sciences, Humanitas University, and Division of Colon and Rectal Surgery, IRCCS Humanitas Research Hospital, Milan, Italy.
² Department of Biomedical Sciences, and IRCCS Humanitas Research Hospital, Milan, Italy.
³ Gastrounit, Medical Division, and Copenhagen Center for Inflammatory Bowel Disease in Children, Adolescents and Adults, Hvidovre Hospital, University of Copenhagen, Denmark.
⁴ Department of Gastroenterology, Lüneburg Hospital, University of Hamburg, Lüneburg, Germany.
⁵ Department of Surgery, Clinic of Visceral and Thoracic Surgery, Cantonal Hospital Winterthur, Zurich.
⁶ Department of Biomedical Engineering, Clinical Research and Artificial Intelligence in Surgery, Faculty of Medicine, University of Basel, Allschwil, Switzerland.
⁷ Department of Gastroenterology, Fakeeh University Hospital, Dubai, UAE.
⁸ Department of Internal Medicine I, Siloah St. Trudpert Hospital, Pforzheim.
⁹ Hannover Medical School, Hannover, Germany.
¹⁰ University Hospital Munster, Department of Medicine B - Gastroenterology and Hepatology, Munster, Germany.
¹¹ Gastroenterology Unit, IIS-IP, Universidad Autónoma de Madrid [UAM], CIBEREHD, Madrid, Spain.
¹² King's College London, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, London, UK.
¹³ Department of Gastroenterology, Dietetics and Internal Medicine, Poznań University of Medical Sciences, and Heliodor Święcicki University Hospital, Poznań, Poland.
¹⁴ Department of Medicine, Division of Gastroenterology, Mater Dei Hospital, Msida, Malta.
¹⁵ Gastroenterology Division, Hospital Beatriz Ângelo, Loures, Portugal.
¹⁶ Department of Biomedical Sciences, Humanitas University, and IBD Center, Humanitas Clinical and Research Center, Milan, Italy.
¹⁷ IBD Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna DIMEC, University of Bologna, Bologna, Italy.
¹⁸ Department of Gastroenterology, Barts Health NHS Trust, Royal London Hospital, London, UK.
¹⁹ Karolinska Institutet, Department of Medicine Solna, and Karolinska University Hospital, Department of Gastroenterology, Dermatovenereology and Rheumatology, Stockholm, Sweden.
²⁰ Department of Colon & Rectal Surgery, Cleveland Clinic, Cleveland, OH, USA.
²¹ Institute of Immunology and Immunotherapy, University of Birmingham, and Division of Gastroenterology, University Hospitals Birmingham NHS Trust, Birmingham, UK.
²² Department of Gastroenterology, Venizeleio General Hospital, Heraklion, Greece.
²³ Department of Gastroenterology and Hepatology, Division of Internal Medicine, University and Medical School of Ioannina, Ioannina, Greece.
²⁴ Department of Gastroenterology, Tel-HaShomer Sheba Medical Center, Ramat Gan, and Sackler Medical School, Tel Aviv, Israel.
²⁵ Division of Gastroenterology, McGill University Health Centre, Montreal, QC, Canada.
²⁶ 1st Department of Medicine, Semmelweis University, Budapest, Hungary.
²⁷ School of Medicine, European University Cyprus, Nicosia, Cyprus.
²⁸ Department of Gastroenterology, University Hospital 'Tsaritsa Yoanna - ISUL', Medical University Sofia, Sofia, Bulgaria.
²⁹ Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Trust, Cambridge, UK.
³⁰ Department of Advanced Medical and Surgical Sciences, Universitá degli Studi della Campania "Luigi Vanvitelli", Naples, Italy, and Colorectal Surgery, Vall d'Hebron University Hospital, Barcelona, Spain.
³¹ Department of Biomedical Sciences, Humanitas University, and IRCCS Humanitas Research Hospital, Milan, Italy.
³² Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
³³ Department of Advanced Medical and Surgical Sciences, Universitá degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
³⁴ Department of Gastroenterology and Hepatology, University Hospitals Leuven, and Department of Chronic Diseases, Metabolism and Ageing, TARGID - IBD, KU Leuven, Leuven, Belgium.
³⁵ Department of Gastroenterology and Centre for Colorectal Disease, St Vincent's University Hospital, Dublin, Ireland.
³⁶ Department of Colorectal Surgery, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Clichy and Université of Paris, France.

PMID: 34635910
DOI: 10.1093/ecco-jcc/jjab177

Abstract

This is the second of a series of two articles reporting the European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on the management of adult patients with ulcerative colitis [UC]. The first article is focused on medical management, and the present article addresses medical treatment of acute severe ulcerative colitis [ASUC] and surgical management of medically refractory UC patients, including preoperative optimisation, surgical strategies, and technical issues. The article provides advice for a variety of common clinical and surgical conditions. Together, the articles represent an update of the evidence-based recommendations of the ECCO for UC.

Keywords: Ulcerative colitis [UC]; inflammatory bowel disease [IBD]; surgery.

MeSH terms

Adult
Colitis, Ulcerative* / drug therapy
Colitis, Ulcerative* / surgery
Consensus
Crohn Disease* / surgery
Humans

Grants and funding

ECCO