Insecticides stand out as the most dangerous pesticides, and many of them can cause cytotoxic and genotoxic effects in organisms. For this reason, a systematic review was performed focusing on the effect of insecticides on Allium cepa system by two ways: (1) a scientometric study to identify trends and gaps in the literature on the evaluation of insecticides to guide future research efforts and (2) a meta-analytical approach compiling the information to obtain an overall result about insecticide effect on A. cepa. It was found that there is an increasing production of articles in this research area. The H-index of our data set was 11, with an average of 13.72 citations per item. The leader country in this research area was India, followed by Turkey and Brazil. The best cited research area was "Environmental Sciences" and "Environmental Sciences and Ecology," followed by "Cell Biology." The most used keywords were genotoxicity, pesticides, and insecticide. The meta-analytical test showed that the number of micronuclei found in onion cells treated with insecticides is higher than that in untreated ones, and the use of pesticides reduced the mitotic index. In conclusion, it is evident the need for more studies about biotechnology, nanotechnology, and biopesticides to develop safer pesticides.
Keywords: CiteSpace; Environment pollution; Micronuclei; Mitotic index; Pesticides; Toxicity.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.