Abstract
Mouse monoclonal antibody 4-I-244 detects a developmentally regulated antigen in embryos of Volvox carteri and inhibits specifically the morphogenetic process of inversion (the process by which the embryo turns inside out). Antigen 4-I-244 was chemically characterized as a complex phytosphingolipid containing the neutral sugars xylose, galactose, and glucose as well as inositol and phosphate.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antibodies, Monoclonal
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Cell Membrane / immunology
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Cell Membrane / physiology
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Chlorophyta / immunology
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Chlorophyta / physiology*
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Chlorophyta / ultrastructure
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Fluorescent Antibody Technique
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Glycosphingolipids / analysis
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Glycosphingolipids / immunology
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Glycosphingolipids / physiology*
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Morphogenesis
Substances
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Antibodies, Monoclonal
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Glycosphingolipids