There are more Hsp90 chaperone mechanisms in heaven and earth, dear reader, than are dreamt of in your philosophy

Eugenia M Clerico; Lila M Gierasch

doi:10.1016/j.molcel.2022.03.040

There are more Hsp90 chaperone mechanisms in heaven and earth, dear reader, than are dreamt of in your philosophy

Mol Cell. 2022 Apr 21;82(8):1403-1404. doi: 10.1016/j.molcel.2022.03.040.

Authors

Eugenia M Clerico¹, Lila M Gierasch²

Affiliations

¹ Department of Biochemistry & Molecular Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA.
² Department of Biochemistry & Molecular Biology, University of Massachusetts Amherst, Amherst, MA 01003, USA; Department of Chemistry, University of Massachusetts Amherst, Amherst, MA 01003, USA. Electronic address: gierasch@biochem.umass.edu.

Abstract

Dahiya et al. (2022) and Biebl et al. (2022) present mechanistic insights into the Hsp40/Hsp70/Hsp90 chaperone teamwork and the co-chaperones that participate in this network.

Publication types

Research Support, N.I.H., Extramural
Comment

MeSH terms

HSP70 Heat-Shock Proteins / genetics
HSP70 Heat-Shock Proteins / metabolism
HSP90 Heat-Shock Proteins* / genetics
HSP90 Heat-Shock Proteins* / metabolism
Molecular Chaperones* / genetics
Molecular Chaperones* / metabolism
Philosophy
Protein Binding

Substances

HSP70 Heat-Shock Proteins
HSP90 Heat-Shock Proteins
Molecular Chaperones

Grants and funding

R35 GM118161/GM/NIGMS NIH HHS/United States