Abstract
T cells with engineered KRAS G12D-specific TCRs mediated regression of metastases in a patient with pancreatic cancer.
©2022 American Association for Cancer Research.
MeSH terms
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Carcinoma, Pancreatic Ductal* / genetics
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Carcinoma, Pancreatic Ductal* / pathology
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Humans
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Pancreatic Neoplasms* / genetics
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Pancreatic Neoplasms* / pathology
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Proto-Oncogene Proteins p21(ras) / genetics
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Receptors, Antigen, T-Cell
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T-Lymphocytes / pathology
Substances
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KRAS protein, human
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Receptors, Antigen, T-Cell
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Proto-Oncogene Proteins p21(ras)