Loss of LPR8 Reduces GPX4 Levels, Resulting in Ferroptosis Sensitivity

Cancer Discov. 2022 Aug 5;12(8):1835. doi: 10.1158/2159-8290.CD-RW2022-109.

Abstract

LPR8 was identified as a factor contributing to ferroptosis resistance in multiple tumor types.

Publication types

  • Comment

MeSH terms

  • Ferroptosis* / genetics
  • Humans
  • Phospholipid Hydroperoxide Glutathione Peroxidase

Substances

  • Phospholipid Hydroperoxide Glutathione Peroxidase